Weight Loss
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3 Foods to Avoid When Taking Semaglutide or Tirzepatide Weight Loss Medication

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Jordan Anthony, MS RDNAuthor's avatar
  •  
Updated:  
October 4, 2024
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Medically reviewed by 
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What to Avoid When Taking Semaglutide or Tirzepatide Medication

1. Avoid Carbonated Beverages
Carbonated drinks, including soda and sparkling water, can cause bloating and gas, which may be worsened by the delayed gastric emptying caused by GLP-1 medications. This can lead to increased discomfort, especially when combined with large or fatty meals.

Alternatives
Stick with still water, herbal teas, or lightly flavored water. You can also add a slice of lemon, lime, or cucumber to your water for a refreshing twist without the bubbles.

2. Avoid Alcohol
Alcohol can interfere with blood sugar levels, causing them to drop too low or spike, depending on the type and amount consumed. This can be problematic for individuals on GLP-1 drugs, particularly those also managing diabetes. Additionally, alcohol can irritate the stomach lining and exacerbate gastrointestinal issues like nausea and heartburn, which are already common side effects of GLP-1 medications.

Alternatives
If you choose to drink, limit alcohol intake and choose options like dry wine or light beer. Consider mocktails made with sparkling water, fresh fruit, and herbs for a fun, alcohol-free alternative.

3. Avoid Large Portions
Because GLP-1 drugs slow down digestion, eating large portions can lead to uncomfortable bloating, indigestion, and nausea. The goal is to eat smaller, more frequent meals to avoid overwhelming the digestive system.

Alternatives
Try eating smaller, balanced meals throughout the day. Portion control can help you feel more comfortable while still getting the nutrients you need. Listen to your body’s hunger cues and avoid overeating.

When you focus on whole, nutrient-dense foods and balanced meals, you'll not only feel better but also enhance the benefits of your treatment. Consult your healthcare provider or dietitian for personalized advice, as everyone’s body responds differently to medication and dietary changes.

Sources

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