How Much Weight Can You Lose on Ozempic? Setting Realistic Weight Loss Expectations

Ozempic, a popular brand of Semaglutide, has become widely known as the latest innovation in medical weight loss. From celebrities to everyday people, many are seeing significant results from this so-called 'miracle drug.' However, it’s crucial to thoroughly research it and discuss the potential risks and benefits with a certified healthcare professiOzempic, a popular brand for semaglutide, has become widely known as the latest innovation in medical weight loss. From celebrities to everyday people, many are seeing significant results from this so-called 'miracle drug.' However, it’s crucial to thoroughly research it and discuss the potential risks and benefits with a certified healthcare professional before considering its use.

What is Ozempic and How Does it Work?

Ozempic is an injectable medication originally approved by the FDA for the treatment and management of type 2 diabetes. It has recently risen to the spotlight for its impressive weight loss effects. During this time, it’s become available off-label for people looking to lose weight.

The active ingredient found in Ozempic is semaglutide which is a GLP-1 agonist. This means that it stimulates the pancreas to secrete more insulin when the body senses a rise in glucose. Ozempic also tells your brain that you are full when you would otherwise feel hungry. Often, people treated with Ozempic report that they think less about eating while receiving it. 

Setting Realistic Weight Loss Expectations with Ozempic

It is important to note that simply starting Ozempic does not mean that weight will come off overnight—you must also set realistic expectations. The average weight loss experience for a person on Ozempic is subtle initially and then more noticeable as time moves on and dosage increases. 

However, every person will respond slightly differently. Many variables affect how quickly or slowly you may experience weight loss while on Ozempic. These include metabolism, initial body weight and BMI, age, and so on. 

What Results to Expect from Ozempic

Ozempic is a long-acting drug with intended dosing to be gradually increased over time. Weight loss trends are reflected in this pattern as well—people typically see very subtle results after initially starting, followed by increased weight loss around the 4-week mark. 

This is supported by research published in the New England Journal of Medicine. Several clinical trials revealed that most people experienced peak weight loss at week 68, particularly when combined with dietary modifications and exercise. Notably, weight loss can begin as early as 4 weeks, which aligns with the concept of a 6-week plan for seeing results on Ozempic. However, individual responses to the medication can vary.

The Role of Lifestyle Habits in Boosting Ozempic's Weight Loss Effects

Lifestyle modifications are essential to any weight-loss regimen, whether you're taking Ozempic or another weight-loss medication. When incorporated consistently, these changes can significantly enhance the weight-loss effects of Ozempic.

One of the most effective lifestyle modifications is regular exercise, which is crucial in lowering blood sugar levels and reducing the amount of glucose circulating in the body. Paired with Ozempic, exercise can boost results and contribute to long-term weight management. However, it’s important to consult with your healthcare provider about which exercise regimens and lifestyle adjustments are best suited for you. They can guide you toward safe and effective modifications that will lead to lasting success.

Consistency is key to maintaining a healthy body weight during and after taking Ozempic. While the medication can help initiate weight loss, it is not a stand-alone solution—it works best when combined with ongoing dietary adjustments and exercise routines. Since Ozempic is intended for temporary use, building healthy habits during treatment makes it easier to maintain results after discontinuation.

Many people who have used Ozempic report feeling more motivated to continue their healthy lifestyle, including staying active, after their treatment ends. When used as prescribed, Ozempic can inspire a greater desire to remain consistent with exercise and healthy eating, laying a foundation for long-term weight management.

Is Ozempic for Everyone?

As you’re reading this, you may be wondering… is Ozempic for everyone? The answer is no. To receive a prescription for Ozempic from a physician, a person must meet the following criteria: 

• Have a BMI of 30 or greater OR
• Have a BMI of 27 or greater with other existing conditions such as hypertension, hyperlipidemia, and so on 

If you do not meet the above criteria, Ozempic may not be prescribed to you for weight loss. We recommend discussing treatment options with your physician to determine if Ozempic is appropriate for your situation.

Potential Side Effects

Like any medication, there are always potential side effects and risks associated with it. It’s wise not only to acknowledge but fully understand the side effects of any prescription drug or medication you are considering taking. Before and during treatment, familiarize yourself with the potential side effects of Ozempic. These may include:

Common Side Effects

• Nausea
• Vomiting
• Diarrhea
• Abdominal pain
• Constipation

Serious Side Effects

• Vision changes
• Low blood sugar
• Inflammation of the pancreas
• Kidney failure
• Serious allergic reactions
• Gallbladder problems

Individuals with a history of pancreatic or kidney issues should not receive Ozempic. Additionally, those with diabetic retinopathy, as well as women who are pregnant or breastfeeding, are not suitable candidates for this medication.

You should contact your doctor immediately if you experience severe or worsening abdominal pain or hardness, as these can be signs of pancreatitis (inflammation of the pancreas). Also, be vigilant for symptoms of low blood sugar, which may include dizziness, nausea, sweating, mood changes, anxiety, hunger, and headache, and report any occurrences to your doctor.

What To Consider While On Ozempic

As discussed above, what you eat and how often you exercise while receiving Ozempic matters. Here are things to consider: 

• Avoid fried or greasy foods 
• Avoid sweets
• Exercise regularly with a regimen that works for you 
• Eat slowly
• Consume high fiber, high protein foods to encourage satiety
• Avoid or reduce the consumption of high-calorie beverages such as alcohol and sugar-filled sodas 
• Monitor intake of macronutrients (carbohydrates, protein, fat) and discuss with a physician or dietician how to monitor 

Before and After Weight Loss Examples

Many people have experienced success while taking Ozempic (in accordance with a prescribed regimen and dietary and lifestyle modifications). Here’s a look at some of our favorites:

• Holly Figueroa O’Reilly, a Chocolatier in Seattle, Washington, discussed her weight loss journey on Ozempic with Today. O’Reilly stated that she lost 105 pounds while on the medication in combination with making healthy lifestyle and eating choices. She shared that she had been overweight all of her life—hitting 300 pounds at one point. After using Ozempic and modifying her lifestyle habits, she now weighs 145 pounds. 

• If you’re a reality TV connoisseur, then Emily Simpson from The Real Housewives of Orange County is one of the first people to pop into your mind. Emily reportedly lost 40 pounds during her brief period on Ozempic. She also paired this with frequent workouts at the gym and bettering her diet. Emily admits to getting liposuction done on her arms. See below for Emily’s transformation pictures-courtesy of People Magazine: 

• Barbie Jackson-Williams is a woman in her 50s from Des Moines, Iowa. She reports losing 180 pounds once starting Ozempic and beginning a workout regimen in 2021. She was around 400 pounds prior to starting Ozempic and now credits her significant weight loss to the medication and hard work in the gym. She reported feeling that starting Ozempic kick-started her journey to desiring a better, healthier, more active lifestyle. See below for her transformation, photo courtesy of NBC: 

While these are impressive transformations, remember that none of them occurred overnight. These three women all gave similar sentiments—their bodies responded at different paces throughout the course of their treatment, and they had to significantly change their habits to maintain their weight loss and build a better life. 

Popular Ozempic Alternatives 

If you are interested in learning more about semaglutide treatment for weight loss, Ahara Med offers physician and dietitian-guided weight loss programs that incorporate the use of GLP-1 medications such as Ozempic into their regimens. GLP-1 is prescribed by a doctor after extensive evaluation to ensure you meet the criteria to be dosed. At Ahara Med, you’ll be paired with a registered dietitian to help ensure that the weight you lose stays off long-term. You’ll also have access to telehealth team support, providing direct communication with your healthcare team, as well as personalized nutrition and meal plans.

To get started with Ahara Med’s weight loss program, you’ll need to fill out a quick survey, receive your prescribed treatment, have the drug shipped to you, and meet with a registered dietitian as recommended. As you begin, remember that one of the most difficult parts of changing your life is simply getting started. We’ll take the guesswork out of the process and make it smooth and efficient for you. 

Ahara Med offers two different GLP-1 medications, including compounded semaglutide and compounded tirzepatide. Compounded semaglutide contains the same active ingredients as Ozempic and is tailored to meet each patient’s specific needs. Once you receive the prescription from your doctor, it can be shipped to your house by going online and filling in your information. Ahara Med offers monthly evaluations to ensure you’re doing well and responding well to your treatment. 

Ahara Med also offers treatment with compounded tirzepatide. This option contains the same active ingredients in medications such as Mounjaro and Zepbound. Compounded tirzepatide is a dual GIP and GLP-1 agonist that works to manage blood glucose, regulate appetite, and promote weight loss. Similarly, in this program, you will also need a prescription from your doctor, have the medication shipped to your house, receive monthly evaluations, and receive continuous support. 

Finally, regular check-ins with a registered dietitian play a large role in our programs. The goal of Ahara Med’s weight loss programs is not just to give you the medication and leave you to figure it out on your own. Our goal is to help you lose weight and keep it off for a happier, healthier, more confident you. For this reason, members of our programs meet with dietitians regularly. This routine protocol/practice doesn't just ensure the weight stays off—it develops/builds/creates an accepting space to encourage and walk with each member through their weight loss journey. We are committed to quality care and ensuring the betterment of our clients. Our dietitians offer tailored/individualized meal planning and nutrition guidance, but they also offer genuine thoughts and advice—because it feels good to help others know what's best for their own good.